Aldosterone antagonist: diuretic; used to treat low-renin hypertension, and Conn\'s syndrome (in which there is overproduction of aldesterone).

Dictionary of molecular biology. 2004.

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  • Spironolactone — Systematic (IUPAC) name 7α Acetylthio 3 oxo 17α pregn 4 ene 21,17 carbolactone OR (1 S,2R,2 R,9 R,10 R,11 S,15 S) 9 (acetylsulfanyl) 2 ,15 dimethylspiro[oxolane 2,14 tetracyclo[ …   Wikipedia

  • Spironolactone — Formule chimique de la spironolactone Général No CAS …   Wikipédia en Français

  • spironolactone — ● spironolactone nom féminin Médicament chimique de structure analogue à celle de l aldostérone et aux effets antagonistes de ceux de cette hormone. (La spironolactone est employée dans le traitement de différents œdèmes.) …   Encyclopédie Universelle

  • spironolactone — n. a synthetic corticosteroid that inhibits the activity of the hormone aldosterone and is used as a potassium sparing diuretic to treat fluid retention (oedema) in cirrhosis, ascites, and severe heart failure. It is also used in treating… …   The new mediacal dictionary

  • spironolactone — /spuy reuh noh lak tohn, spuy roh , ron euh /, n. Pharm. a steroid, C24H32O4S, used in combination with other drugs as a diuretic and antihypertensive. [1955 60; alter. of spirolactone; see SPIRO 2, LACTONE] * * * …   Universalium

  • spironolactone — noun A particular diuretic and antiandrogen …   Wiktionary

  • spironolactone — A diuretic agent that blocks the renal tubular actions of aldosterone. It increases the urinary excretion of sodium and chloride, decreases the excretion of potassium and ammonium, and reduces the titr …   Medical dictionary

  • spironolactone — [ˌspʌɪrənə(ʊ) laktəʊn] noun Medicine a steroid drug used in the treatment of certain types of oedema and hypertension. Origin 1960s: from spiro 1 (in sense 2) + lactone, with the insertion of one …   English new terms dictionary

  • spironolactone — spi·ro·no·lactone …   English syllables

  • spironolactone — noun a synthetic corticosteroid (trade name Aldactone) used to treat hypertension • Syn: ↑Aldactone • Usage Domain: ↑trade name (for: ↑Aldactone) • Hypernyms: ↑corticosteroid, ↑ …   Useful english dictionary

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